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Dr. Nicholas Franco, MD, Explains Testosterone Replacement Therapy in Men

Michigan, US, 9th July 2024, ZEX PR WIRE, Testosterone replacement therapy (TRT) has garnered considerable attention as a treatment option for men experiencing symptoms associated with low testosterone levels. Dr. Nicholas Franco, a distinguished retired urologist with extensive experience in male health, explains what TRT is, its benefits, and the potential risks associated with the therapy.

Understanding Testosterone Replacement Therapy

Dr. Nicholas Franco says testosterone is a vital hormone in men, responsible for the development of male characteristics and overall well-being. As men age, Dr. Franco says, their testosterone levels naturally decline, leading to a condition known as hypogonadism or low testosterone. Symptoms of low testosterone can include fatigue, decreased libido, mood changes, and reduced muscle mass.

Testosterone replacement therapy, he says, aims to restore normal testosterone levels in men who have been diagnosed with low testosterone. The treatment can be administered through various forms, including injections, patches, gels, and implants. The goal of TRT is to alleviate symptoms of low testosterone and improve quality of life.

Benefits of Testosterone Replacement Therapy

TRT offers several significant benefits for men with low testosterone levels. Dr. Franco emphasizes that one of the primary advantages of TRT is energy restoration. Men undergoing TRT often report a marked increase in their energy levels, allowing them to engage more actively in daily activities and exercise routines. This boost in energy can lead to overall improved physical health and well-being.

Another critical benefit of TRT, Dr. Franco says, is enhanced mental focus and alertness. Low testosterone levels are often associated with cognitive decline, including difficulties in concentration and memory. By restoring testosterone to normal levels, TRT can help improve mental clarity and focus, making it easier for men to stay engaged and productive in their personal and professional lives.

Sexual function, Dr. Nicholas Franco adds, is another area where TRT can have a profound impact. Men with low testosterone, Dr. Franco says, frequently experience a decline in libido and sexual performance. TRT, he notes, can help restore sexual desire and improve erectile function, contributing to a healthier and more satisfying sex life. This improvement in sexual health can also have positive effects on emotional intimacy and overall relationship satisfaction.

Risks Associated with Testosterone Replacement Therapy

While TRT offers numerous benefits, it has potential risks. Dr. Franco highlights several risks that men should consider before starting therapy. One of the risks is the possible worsening of sleep apnea, a condition characterized by interrupted breathing during sleep. Testosterone therapy can exacerbate sleep apnea, leading to poorer sleep quality and associated health problems.

Another potential side effect of TRT, he says, is the development of acne. Increased testosterone levels can stimulate sebaceous glands, leading to oily skin and acne outbreaks. For some men, this can be a minor inconvenience, while for others, it may require additional skin care treatments.

Prostate health, Dr. Franco notes, is also a significant concern when considering TRT. Testosterone can stimulate the growth of the prostate, which may lead to noncancerous enlargement of the prostate gland, known as benign prostatic hyperplasia (BPH). Men with a history of prostate issues should discuss the potential risks with their healthcare provider before starting TRT.

Additionally, Dr. Franco says TRT can cause breast enlargement (gynecomastia) and testicular shrinkage. These side effects result from hormonal imbalances caused by increased testosterone levels and can be distressing for some men. He notes that close monitoring and management by a healthcare provider can help mitigate these effects.

Blood clots, Dr. Franco states, are another severe risk associated with TRT. Elevated testosterone levels can increase the risk of developing blood clots, which can lead to deep vein thrombosis (DVT) or pulmonary embolism (PE). These conditions are potentially life-threatening and require immediate medical attention.

The Importance of Medical Supervision

Dr. Franco points to the importance of undergoing TRT under the supervision of a qualified healthcare provider. Proper diagnosis and monitoring are crucial to ensuring the safe and effective use of testosterone therapy. He says regular blood tests and follow-up appointments can help manage side effects and adjust treatment.


Testosterone replacement therapy, Dr. Franco concludes, offers significant benefits for men suffering from low testosterone levels, including restored energy, improved mental focus, and enhanced sexual function. However, it is essential to weigh these benefits against the potential risks, such as worsening sleep apnea, acne, prostate enlargement, breast enlargement, testicular shrinkage, and blood clots.

Dr. Nicholas Franco’s extensive experience in urology and male health highlights the importance of informed decision-making and medical supervision when considering TRT. By understanding the benefits and risks, men can make educated choices about their health and well-being. As with any medical treatment, Dr. Franco says, personalized care and ongoing monitoring are crucial to achieving the best possible outcomes.

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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Euro Tidings journalist was involved in the writing and production of this article.